Druggie paranoia in the near future, when the drug du jour is Substance D (for Death) and the only cure is the torturous New-Path rehab center. Richard Linklater's adaptation of a Philip K. Dick novel avails itself of the rotoscope animation technique of his Waking Life, live-action photography covered over in a paint-by-numbers style. The undulating drawing doesn't disguise the bad performances (Keanu Reeves, Robert Downey, Jr., and Woody Harrelson, all perfectly recognizable under the paint), but it creates some noteworthy effects: the full-body "scramble suit" that conceals the wearer's identity behind a continuously shape-shifting mask; a couple of hallucinatory monsters; Winona Ryder's long-awaited first "nude" scene. (2006) — Duncan Shepherd
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